I’d love to get paid to test experimental drugs. So far it’s only cost me money.
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deranger@sh.itjust.worksto
World News@lemmy.world•U.S. launches large-scale strikes on ISIS targets across SyriaEnglish
72·4 days agoNo. If Russia and Syria are allies why is the US bombing there? Probably because Russia can’t because their military is both broke and broken.
To be clear I’d prefer no military interventions at all, but if they’re going to happen, I can at least enjoy seeing Russia’s complete lack of response. It’s telling.
deranger@sh.itjust.worksto
World News@lemmy.world•U.S. launches large-scale strikes on ISIS targets across SyriaEnglish
253·4 days agoIran, Venezuela, Syria… I’m seeing a pattern here. Which allies of Russia remain?
It’s slightly more lipophilic, not heavily so. The main draw of meth from a pharmacodynamic perspective is that it slows enzymatic degradation (you’re high longer). On a mg for mg basis dextroamphetamine is actually stronger than meth.
Tooth decay is caused by dry mouth and poor hygiene. The added methyl group doesn’t affect this aspect.
That’s because it doesn’t do any of that.
You’re not comprehending what you’re reading. In that sentence, when it says it modulates the pro-inflammatory and anti-inflammatory response, it’s saying it affects both, It’s not saying that the nervous system itself is pro-inflammatory.
Together, these results uncovered two lines of signalling from the vagal ganglia to the brain. One line (TRPA1) carries anti-inflammatory signals and acts on cNST neurons to enhance the anti-inflammatory response (for example, by positive feedback onto immune cells releasing anti-inflammatory cytokines) and helps to suppress the pro-inflammatory state. The other (CALCA neurons) responds to pro-inflammatory signals and helps to tune down the pro-inflammatory response (for example, by negative feedback onto immune cells releasing pro-inflammatory cytokines).
To “tune down a pro-inflammatory response” and “enhance an anti-inflammatory response” are both anti-inflammatory effects achieved through modulating both anti- and pro- inflammatory responses. Enhance one, diminish another.
We demonstrate that pro-inflammatory and anti-inflammatory cytokines communicate with distinct populations of vagal neurons to inform the brain of an emerging inflammatory response.
Where do you think those cytokines that are influencing the nervous system come from? White blood cells. That’s where it all starts, not the nervous system. You’re putting the cart before the horse.
Chemogenetic activation of the cNST neurons during an immune response suppresses inflammation.
The study you linked demonstrates the brain suppresses inflammation/fever, not promotes it.
The brain is not responsible for fevers, the immune system is.
deranger@sh.itjust.worksto
Science Memes@mander.xyz•Humans are part of the ecosystem.English
23·6 days agoSo profits is a main driver
This is exactly what I’m getting at. If these groups of humans were placed in the same scenarios that Europeans or other westerners were placed in, would they not be susceptible to the same greed that motivated them?
I do not deny that many native societies appear to live in more harmony with the environment than your average westerner. There is certainly a lot to learn there, and I believe we would do better if we emulated some of those characteristics. However, I think that we’re all susceptible to the same flaws, as we are all human.
Ultimately what I’m saying is I don’t think that natives have some superpower where they have figured out how to escape the flaws that have plagued humanity for thousands of years.
deranger@sh.itjust.worksto
Science Memes@mander.xyz•Humans are part of the ecosystem.English
341·6 days agoThank you for providing sources.
deranger@sh.itjust.worksto
Science Memes@mander.xyz•Humans are part of the ecosystem.English
11118·6 days agoThis reeks of the “noble savage” stereotype. I would be willing to bet 80% of biodiversity being in native lands has more to do with how brutally they’ve been repressed than how “in tune” with the environment they are.
They’re people too, and I see little reason to believe they wouldn’t fall to the same human flaws as the rest of us if given the chance.
deranger@sh.itjust.worksto
Technology@lemmy.world•200 million records exposed in massive Pornhub data breach — here’s what we know so farEnglish
1·7 days agoRAM is insane but storage is cheap. You can get recertified drives for a NAS for like $16/TB.
deranger@sh.itjust.worksto
Videos@lemmy.world•The true story of Martin Heemeyer, and the Killdozer.
4·7 days agoCheck out the rest of Well There’s Your Problem, it might just save your life some day. (Technically this is pre-WTYP but I still count this as one of the first bonus episodes)
If you’re only counting New York City proper this is true, but the New York City metro area vastly out populates the entire nation of Sweden. (20M vs 10M)
deranger@sh.itjust.worksto
Technology@lemmy.world•200 million records exposed in massive Pornhub data breach — here’s what we know so farEnglish
5·8 days agoJust download everything, storage is cheap. No reason not to have a few TB of high resolution porn of exactly what you like.
You’re right, I was mistaken.
deranger@sh.itjust.worksto
World News@lemmy.world•Trump says Venezuela is 'turning over' up to 50 million barrels of oil to USEnglish
4·8 days agoTo paraphrase Omar from The Wire, “Oil ain’t got no owners, only vendors.”
That’s US domestic crude which is famously volatile. I’d be curious to see what Venezeula’s oil is like. I’ve heard it’s similar to the shitty heavy crude from the Middle East, which the US has facilities to process, unlike the domestic oil they produce which has to be processed elsewhere.
deranger@sh.itjust.worksto
Technology@lemmy.world•Dell brings back XPS laptops — ditches the capacitive touch bar, adds 1Hz display option, and upgrades 14 and 16-inch modelsEnglish
3·8 days agoWhat you’re describing is AMOLED. Nobody calls them TFT OLEDs.





It’s getting to the point I’d rather die than be complicit.